Publications



Untitled


Untitled


Metabolic dysregulation in Vitamin-E and carnitine shuttle energy mechanisms associate with human frailty


Nicholas J. W. Rattray, Drupad K. Trivedi, Yun Xu, Tarani Chandola, Caroline H. Johnson, Alan D. Marshall, Krisztina Mekli, Zahra Rattray, Gindo Tampubolon, Bram Vanhoutte, Iain R. White, Frederick C. W. Wu, Neil Pendleton, James Nazroo, Royston Goodacre

Nature Communications, vol. 10(1), 2019 Nov 1


Evaluation of temporal aggregation processes using spatial intensity distribution analysis


Zahra Rattray, Egor Zindy, Karen M. Buzza, Alain Pluen

2019 Aug 23, pp. 141-155


Abstract 2773: A DNA-damaging lupus autoantibody synergizes with PARP inhibitors against DNA repair-deficient tumor cells


Zahra Rattray, Jaymin M. Patel, Phillip W. Noble, Valentina Dubljevic, Deanne L. Greenwood, James A. Campbell, James E. Hansen

Cancer Research, vol. 78, 2018 Jun 1, pp. 2773-2773


Compositions and methods for enhancing nuclear translocation


Zahra Rattray, James E. Hansen

2018 Jan 1


Re-engineering and evaluation of anti-DNA autoantibody 3E10 for therapeutic applications


Zahra Rattray, Valentina Dubljevic, Nicholas J.W. Rattray, Deanne L. Greenwood, Caroline H. Johnson, James A. Campbell, James E. Hansen

Biochemical and Biophysical Research Communications, vol. 496(3), 2018 Jan 1, pp. 858-864


Metabolomics guided pathway analysis reveals link between cancer metastasis, cholesterol sulfate, and phospholipids.


Caroline H. Johnson, Antonio F. Santidrian, Sarah E. LeBoeuf, Michael E. Kurczy, Nicholas J. W. Rattray, Zahra Rattray, Benedikt Warth, Melissa Ritland, Linh T. Hoang, Celine Loriot, Jason Higa, James E. Hansen, Brunhilde H. Felding, Gary Siuzdak

Cancer and Metabolism, vol. 5(1), 2017 Nov 1


Binding proteins 2


Zahra Rattray, James Hansen, James Campbell, Valentina Dubljevic, Deanne Greenwood

2017 Jun 1


Environmental influences in the etiology of colorectal cancer: the premise of metabolomics


Nicholas J. W. Rattray, Georgia Charkoftaki, Zahra Rattray, James E. Hansen, Vasilis Vasiliou, Caroline H. Johnson

Current Pharmacology Reports, vol. 3(3), 2017 May 1, pp. 114-125


Evaluation of aggregate and silicone-oil counts in pre-filled siliconized syringes: An orthogonal study characterising the entire subvisible size range.


Maryam Shah, Zahra Rattray, Katie Day, Shahid Uddin, Robin Curtis, Christopher F. van der Walle, Alain Pluen

International Journal of Pharmaceutics, vol. 519(1), 2017 Feb 1, pp. 58-66


Characterisation of Stress‐Induced Aggregate Size Distributions and Morphological Changes of a Bi‐Specific Antibody Using Orthogonal Techniques


Zahra Hamrang, Maryam Hussain, Katie Tingey, Malgorzata Tracka, José R. Casas-Finet, Shahid Uddin, Christopher F. van der Walle, Alain Pluen

Journal of Pharmaceutical Sciences, vol. 104(8), 2015 Jul 1, pp. 2473-2481


Quantitative Assessment of P-Glycoprotein Expression and Function Using Confocal Image Analysis


Zahra Hamrang, Yamini Arthanari, David Clarke, Alain Pluen

Microscopy and Microanalysis, vol. 20(5), 2014 Sep 1, pp. 1329-1339


Taking your breath away: metabolomics breathes life in to personalized medicine


Nicholas J.W. Rattray, Zahra Hamrang, Drupad K. Trivedi, Royston Goodacre, Stephen J. Fowler

Trends in Biotechnology, vol. 32(10), 2014 Sep 1, pp. 538-548


Monitoring the kinetics of CellTrace™ calcein red-orange AM intracellular accumulation with spatial intensity distribution analysis.


Zahra Hamrang, Hayley J. McGlynn, David Clarke, Jeffrey Penny, Alain Pluen

Biochimica et Biophysica Acta, vol. 1840(9), 2014 Aug 1, pp. 2914-2923


On the Cellular Uptake and Membrane Effect of the Multifunctional Peptide, TatLK15


Myasar Alkotaji, Alain Pluen, Egor Zindy, Zahra Hamrang, Harmesh Aojula

Journal of Pharmaceutical Sciences, vol. 103(1), 2014 1, pp. 293-304


Real-time evaluation of aggregation using confocal imaging and image analysis tools


Zahra Hamrang, Egor Zindy, David Clarke, Alain Pluen

Analyst, vol. 139(3), 2014 1, pp. 564-568


Proteins behaving badly: emerging technologies in profiling biopharmaceutical aggregation.


Zahra Hamrang, Nicholas J.W. Rattray, Alain Pluen

Trends in Biotechnology, vol. 31(8), 2013 Jul 1, pp. 448-458


The application of image analysis extensions to processes of relevance to drug development


Zahra Hamrang

[Thesis]. Manchester, UK: The University of Manchester; 2013., 2013 May 5


Raster image correlation spectroscopy as a novel tool for the quantitative assessment of protein diffusional behaviour in solution.


Zahra Hamrang, Alain Pluen, Egor Zindy, David Clarke

Journal of Pharmaceutical Sciences, vol. 101(6), 2012 May 1, pp. 2082-2093


Quantification of P-glycoprotien Expression using spatial intensity distribution analysis


Z Hamrang, A Pluen, E Zindy, DJ Clarke

In: European Microscopy Congress 2012; Manchester. 2012., 2012 1

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